Obesity in children and drug dosing
According to the Australian Institute of Health and Welfare, 25% of children and adolescents are classified as obese. Given that we rely on weight for drug dosing, how do we ensure that we keep our patients safe whilst still delivering effective drug doses?
What drugs doses should be adjusted and how should we do this?
Unfortunately, different drugs require different adjustments - it's all based on the drug's pharmacokinetics. There are however excellent resources online to help us with this.
As a rough guide we can dose drugs according to: -
This document from a hospital in the UK discusses this issue further and provides lists of drugs that should be dosed according to total, ideal or adjusted body weight.
Dr Danielle Scarfe